Evaluation of Mesotherapy and Diode Laser for Gingival Depigmentation: An Ambispective Study
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- Reduction in gingival pigmentation, measured using the Dummett Oral Pigmentation Index (DOPI)
研究概览
简要总结
Non-surgical approaches as well as surgical intervention have been proposed for the management of melanin pigmentation. The surgical approaches depend mainly on the de-epithelization of the target region. It could be performed utilizing various techniques as free gingival grafts, gingivectomy or de-epithelialization using bur abrasion, surgical blade, laser and cryosurgery. Laser especially diode laser was the most frequently used technique and showed better esthetic outcomes, less pain, faster healing and most important patients’ preference and satisfaction after treatment. However, lasers were associated with more recurrence at 6-month follow-up. Therefore, there is a need to other
minimally invasive non-surgical therapeutic option in order to depigment such conditions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects of either gender between the age range of 20-40 years
- •Physiological gingival pigmentation in anterior maxillary and mandibular region
- •DOPI score between 1-3
- •ASA grade 1 individuals.
排除标准
- 未提供
结局指标
主要结局
Reduction in gingival pigmentation, measured using the Dummett Oral Pigmentation Index (DOPI)
时间窗: Absence of re-pigmentation at 3-month follow-up
Absence of repigmentation, assessed through clinical examination
时间窗: Absence of re-pigmentation at 3-month follow-up
次要结局
未报告次要终点
研究者
Nirav Vyas
All India Institute of Medical Sciences, New Delhi