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临床试验/NCT02990949
NCT02990949终止不适用

The Impact of the Timing of Trigger on IVF Success: Randomized Control Trial

Colorado Center for Reproductive Medicine1 个研究点 分布在 1 个国家目标入组 29 人开始时间: 2016年11月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
终止
入组人数
29
试验地点
1
主要终点
Euploid Embryos: the percentage of euploid embryos produced as analyzed by comprehensive chromosomal screening, of total embryos tested

研究概览

简要总结

The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
26 Years 至 44 Years(Adult)
性别
Female
接受健康志愿者
是

入选标准

  • •Planning to move forward with an IVF cycle
  • •Have met the requirements of being a patient at CCRM Colorado
  • •AMA: 39-44 years old And/or
  • •DOR: AMH < 1 & FSH >10 (age independent)

排除标准

  • •Contraindication for pregnancy
  • •Have not fulfilled requirements for IVF cycle
  • •Single gene couple or chromosomal rearrangement
  • •Severe male factor or testicular surgical sperm removal (need sufficient sperm for ICSI)
  • •One ovary
  • •Uterine anomalies
  • •Stage III or IV endometriosis
  • •Explained recurrent miscarriage
  • •PCO or PCOS
  • •Using donor oocyte or gestational carrier

研究组 & 干预措施

Testing group

Experimental

Timing of trigger at end of ovarian stimulation in an IVF cycle: trigger when 2 follicles reach 18mm, OR 1 follicle reaches 18mm AND 1 follicle is between 16-18mm.

干预措施: Timing of trigger (Other)

Control group

No Intervention

结局指标

主要结局

Euploid Embryos: the percentage of euploid embryos produced as analyzed by comprehensive chromosomal screening, of total embryos tested

时间窗: 4 weeks after egg retrieval

次要结局

  • Live birth outcomes: the incidence of pregnancy resulting in live birth following embryo transfer of embryos produced by this IVF cycle(9 months after frozen embryo transfer)
  • Egg maturation: the proportion of mature eggs of total number of eggs retrieved(1 week after egg retrieval)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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The Impact of the Timing of Trigger on IVF Success | 临床试验