Effects of Beef Protein Consumption on Energy Intake - The Protein Leverage Hypothesis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Body weight change
研究概览
简要总结
The purpose of this study is to determine ad libitum daily energy intake, body weight changes and appetite profile in response to protein/carbohydrate and fat ratio over 12 consecutive days, and in relation to age, gender, body mass index (BMI) and fat mass and obesity-associated (FTO) gene alleles.
详细描述
The protein leverage hypothesis requires specific evidence whether energy intake would depend on a possible protein intake target in humans. Meat protein as complete protein may show most beneficial effects on variables regarding food intake regulation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-70 years
- •BMI 18-35 kg/m2
- •Non-smoking
- •Weight stable
排除标准
- •Use of medication
- •More than moderate alcohol consumption
- •Vegetarian
结局指标
主要结局
Body weight change
时间窗: 11 days
Body weight will be measured on day 1, 6 and 12. Subsequently, the change in body weight over time will be calculated.
Appetite profile
时间窗: 12 consecutive days
Appetite profile will be measured by means of questionnaires: visual analogue scales (VAS). Area under the curve (AUC) will be calculated over 12 consecutive days.
Energy intake
时间窗: 12 consecutive days
Total energy intake over 12 days will be determined for each subject by adding energy intake during meals to energy intake from snack consumption.
次要结局
未报告次要终点
研究者
Eveline Martens
PhD student
Maastricht University Medical Center