Social Behavior in Depression
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Valuation of social information
研究概览
简要总结
In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age range between 18 and 60
- •Education experience above high school
- •Score for Hamilton's Depression Scale >=17
- •Diagnosis of depression through Scid
排除标准
- •Undergoing electric shock treatment in 3 months
- •Excluding those who with bipolar disorder
- •Excluding those who with postpartum depression
- •Excluding those who with hysteria
结局指标
主要结局
Valuation of social information
时间窗: Baseline
The valuation of social information was measured by psychological paradigm, developed from animal studies, called "pay-per-view". The participants will be asked make decision about more social information or more monetary reward.
Emotion recognition
时间窗: Baseline
After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.
Cognitive flexibility
时间窗: Baseline
Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.
Optimism bias
时间窗: Baseline
Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.
Prosocial behavior
时间窗: Baseline
The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.
Model-free & model-based tendency
时间窗: Baseline
Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.
次要结局
未报告次要终点
研究者
ma, yina
Principal Investigator
Beijing Normal University