Effect of 12-month daily resveratrol supplementation on brain health in post-menopausal women

niversity of Newcastle0 个研究点目标入组 170 人开始时间: 2016年5月25日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•Women aged 45-85 years old. Post-menopausal (cessation of menses for > 12 months), with no change in medication type or dose for 3 months before the intervention.

•Consuming HRT or seeking alternative therapy for the relief of postmenopausal symptoms (within the past three months).
•Pregnant or breastfeeding.
•Clinic BP >160mmHg systolic or 100mmHg diastolic (determined at screening).
•BMI>40kg/m2 (determined at screening).
•History of breast or cervical cancer, mastectomy or hysterectomy (not due to prolapse).
•Smokers or currently on nicotine therapy.
•Neurological conditions.
•Kidney/liver disease.
•Insulin therapy.
•Warfarin therapy.
•Regularly consuming more than four standard alcoholic drinks per day.
•Major depression as diagnosed by a health care professional.
•Illiterate.
•Physical difficulty that will impede motor and locomotive performance.
•Unable to walk without assistance from people (walking aids okay).
•Unwilling to maintain pre-enrolment physical activity levels and dietary habits for the duration of the trial.
•Unwilling to refrain from consuming stimulants before each clinic visit.
•Currently consuming resveratrol containing supplements.
•Have any other medical condition or treatments (including supplements) which, in the investigators’ opinion, may confound the outcome of the study.

发起方

niversity of Newcastle