Évaluation de l'Impact du Compressed Sensing Sur le Signal QSM
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- concordance of QSM signal with and without compressed-sensing in white matter
研究概览
简要总结
Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which a maximum of four additional 25-minute sequences will be added.
MRI of routine care includes at least the following sequences:
- 3D T1 TFE (2 minutes)
- T2 TSE (2 minutes)
- 3D FLAIR (3 minutes)
The sequences added by the research lasting 25 minutes are:
- SWI QSM 1.0iso 8 echoes (10 minutes)
- SWI QSM 1.0iso 8 echoes CS 6 (7 minutes)
- SWI QSM 1.0iso 8 echoes CS 9 (5 minutes)
- SWI QSM 1.0iso 8 echoes CS 12 (3 minutes)
详细描述
Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which a maximum of four additional 25-minute sequences will be added.
MRI of routine care includes at least the following sequences:
- 3D T1 TFE (2 minutes)
- T2 TSE (2 minutes)
- 3D FLAIR (3 minutes)
The sequences added by the research lasting 25 minutes are:
- SWI QSM 1.0iso 8 echoes (10 minutes)
- SWI QSM 1.0iso 8 echoes CS 6 (7 minutes)
- SWI QSM 1.0iso 8 echoes CS 9 (5 minutes)
- SWI QSM 1.0iso 8 echoes CS 12 (3 minutes)
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •For patients with MS:
- •Patient over 18 years old
- •Presenting MS defined according to McDonald's revised criteria for spatial and temporal clinical or radiological dissemination [16],
- •Should benefit as part of the care of an MRI examination with or without injection of gadolinium
- •Express consent to participate in the study
- •Affiliate or beneficiary of a social security scheme
- •For patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS disease:
- •Patient over 18 years old
- •Should benefit as part of the care of an MRI examination with or without injection of gadolinium
- •Express consent to participate in the study
- •Affiliate or beneficiary of a social security scheme
排除标准
- •For patients with MS:
- •Patient benefiting from a legal protection measure
- •Pregnant or breastfeeding woman
- •For patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS disease:
- •Patient benefiting from a legal protection measure
- •Pregnant or breastfeeding woman
- •Patient with inflammatory and / or demyelinating pathology of the CNS
- •Secondary exclusion criteria :
- •Motion artefact not allowing interpretation of images
- •Patient who did not perform one of the following sequences: 3D T1 TFE, 3D FLAIR (for MS patients), SWI QSM 1.0iso 8 echoes.
- •Secondarily excluded patients will be replaced.
结局指标
主要结局
concordance of QSM signal with and without compressed-sensing in white matter
时间窗: 1 DAY
concordance of QSM signal with and without compressed-sensing in white matter
次要结局
未报告次要终点