Dynamic Thoracic Impedance as a Marker for Heart Failure Decompensation: A Pilot Trial of the "Dynamic Thoracic Impedance Bed Rest Test"
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- Change from sitting to supine to standing in thoracic impedance
研究概览
简要总结
This pilot study proposes to perform measurements of approved thoracic impedance technology that will help answer questions in patients with decompensated heart failure.
详细描述
Improved metrics derived from the transthoracic impedance (Z) available from implanted Medtronic devices may provide more sensitive indicators of the state of compensation for heart failure patients. Quantification of specific data may provide new information that can improve quality of life for patients and offer vital information to clinicians regarding the adequacy of inpatient and outpatient assessment and management of acute decompensated heart failure.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with systolic dysfunction
- •Able to provide informed consent
- •Have a Medtronic manufactured device with Thoracic Impendence Monitoring capabilities
排除标准
- •Patients with severe congestive heart failure who are intubated
- •Patients who are oxygen dependent on continuous positive or bilevel positive ventilation
- •Inability to tolerate postural variations due to congestive heart failure or other medical or surgical condition.Unable to complete proposed testing
- •Subjects who cannot giveWill not give written, informed consent on their own behalf
结局指标
主要结局
Change from sitting to supine to standing in thoracic impedance
时间窗: Baseline, 30 Days
thoracic impedance will be measured at each position at baseline visit then again at the follow-up visits through 30 days
次要结局
- Rate of change in thoracic impedance(Baseline, 30 days)
研究者
Charles Porter, MD
Clinical Associate Professor
University of Kansas Medical Center