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临床试验/EUCTR2016-004545-91-NL
EUCTR2016-004545-91-NL进行中(未招募)1 期

Continuous use of Oral contraceptives as an alternative for long term Pituitary down-regulation with GnRH agonist prior to IVF/ICSI in Endometriosis patients: a randomised controlled trial (COPIE trial) - COPIE trial

VU University Medical Center, department of reproductive Medicine0 个研究点目标入组 330 人开始时间: 2016年12月7日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
330

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
Female

入选标准

  • - Patients with presence of endometriosis (ASRM III-IV) confirmed by previous surgery or likely to be present based on TVUS or MRI (including presence of uni- or bilateral ovarian endometrioma and deep endometriosis).
  • - First, second or third IVF or ICSI cycle
  • - Signed informed consent
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 330
  • F.1.3 Elderly (>=65 years) no
  • F.1.3.1 Number of subjects for this age range

排除标准

  • - Patients aged over 41 years (excluding patients from the day they have celebrated their 41 year birthday)
  • - Patients with known contraindications for oral contraceptives (history of venous trombo-embolic events, positive family history for venous trombo-emblic events and/or known thrombophilic abnormalitie) or GnRH agonists
  • - Pregnancy
  • - Malignancy
  • - Azoospermia in partner/donor

研究者

发起方
VU University Medical Center, department of reproductive Medicine

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