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临床试验/NCT07171255
NCT07171255招募中不适用

Improving Exercise Adherence With App Technology for At-Risk Adults Living in Rural Kansas and Nebraska

Creighton University4 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2025年8月22日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
54
试验地点
4
主要终点
Systolic Blood Pressure

研究概览

简要总结

Alzheimer's disease and related dementias are a public health crisis impacting individuals across the world. In the United States, adults living in rural areas face an elevated risk for cognitive impairment mainly due to disparities in care, higher sedentary behavior, and reduced education. This project proposes to assess the impact of a remotely delivered exercise program (i.e., RemoteEx+) through a smartphone application. The app is programmed by our team and provides video demonstrations of exercises, workout regimes, motivational messaging, and weekly ADRD risk reduction education. The project aims to assess with a pre/post design the following aims:

  • Aim 1. Assess the RemoteEx+ intervention exercise adherence, efficacy, enjoyment, and quality of life. We hypothesize that rural adults will report high exercise adherence (80% of session adherence), efficacy (>50% on Self Efficacy for Exercise), and enjoyment (>5.0 on Intrinsic Motivation Inventory - Interest / Enjoyment Subscale) and that these variables will be positively correlated with quality of life scores (36-Item Short Form Health Survey [SF-36])
  • Aim 2. Determine the impact of a technology-driven exercise program on blood pressure and functional mobility associated with dementia risk. We hypothesize that the exercise program will result in improvements in blood pressure and functional mobility (2-minute step test and 30-second chair rise test) and that participants with high exercise adherence will see the greatest improvements in biomarkers associated with reduced dementia risk.
  • Aim 3. Reduce health disparities among rural-dwelling Nebraska and Kansas residents. We hypothesize that RemoteEx+ will reduce barriers to exercise (Barriers to Being Active Quiz and improve knowledge surrounding dementia and modifiable risk factors (Dementia Knowledge Assessment Tool - Version 2 [DKAT2]) that will result in fewer lifestyle-related health disparities for the communities involved in this study.

The results from this project will inform whether RemoteEx+ has an impact on the stated outcomes above for adults living in rural areas.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
40 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 40-85 years
  • Characterized as underactive by the Telephone Assessment of Physical Activity (TAPA)50
  • Self-reported proficiency in English
  • Own a smartphone and willing to download an application
  • Primary care provider clearance to participate for those who do not pass the PAR-Q+51
  • Live in a rural area (Rural-Urban Commuting Area [RUCA] Codes) 52

排除标准

  • Contraindications to high-intensity exercise
  • Cognitive impairment (<19 on the Telephone Montreal Cognitive Assessment [MoCA])
  • Neurodegenerative or acute neurological diagnoses (e.g., Parkinson's disease, stroke, traumatic brain injury)
  • Orthopedic surgery or injuries in the last 6 months

结局指标

主要结局

Systolic Blood Pressure

时间窗: Baseline and Week 16

次要结局

  • Cardiovascular Endurance(Baseline and Week 16)
  • Lower Extremity Strength(Baseline and Week 16)
  • Exercise Adherence(Baseline and Week 16)
  • Exercise Efficacy(Baseline and Week 16)
  • Quality of Life Improvement(Baseline and Week 16)
  • Barriers to Being Active(Baseline and Week 16)
  • Knowledge of dementia(Baseline and Week 16)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (4)

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