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临床试验/NCT05816967
NCT05816967撤回不适用

Rationalisation of Polypharmacy by the RASP-instrument (Rationalisation of Home Medication by an Adjusted STOPP-list and Discharge Counselling of Geriatric Inpatients: a Prospective, Clinical Trial

Universitaire Ziekenhuizen KU Leuven2 个研究点 分布在 1 个国家开始时间: 2018年10月最近更新:
适应症

试验速览

阶段
不适用
状态
撤回
试验地点
2
主要终点
Acceptance rate of the pharmacotherapeutic recommendations, provided by the clinical pharmacist by the general practitioner.

研究概览

简要总结

Systematic evaluation of polypharmacy in geriatric patients, through a validated list by a clinical pharmacist. The goal is reduction of potentially inappropriate medications (PIMs). A brief counseling session with the patient and/or his/her caregiver will be part of the intervention.

详细描述

This project is focused on the systematic evaluation of polypharmacy in older patients admitted to the acute geriatric wards of a university hospital. Polypharmacy will be identified through a validated list by a clinical pharmacist. The goal is reduction of potentially inappropriate medications (PIMs). Before hospital discharge the hospital pharmacist will have a brief counseling session with the patient and/or his/her caregiver in order to discuss the medication list and to enhance compliance.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
75 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Informed consent by the patient and/or his/her caregiver
  • Admission through the emergency department of patients coming from home or a residential care facility

排除标准

  • Patients not speaking Dutch
  • Patients admitted for end of life care
  • Patients not taking any drugs on admission

结局指标

主要结局

Acceptance rate of the pharmacotherapeutic recommendations, provided by the clinical pharmacist by the general practitioner.

时间窗: 3 month (90 days) after discharge

Acceptance rate of the pharmacotherapeutic recommendations, provided by the clinical pharmacist by the general practitioner.

次要结局

  • Number of falls during hospitalization(During the index hospitalization, from admission on the emergency ward until discharge from the geriatric ward, assessed within 72 hours after discharge.)
  • Number of fractures during hospitalization(during the index hospitalization, from admission to the emergency ward until discharge from the geriatric ward, assessed within 72 hours after discharge.)
  • Length of stay(During the index hospitalization, from admission to the emergency ward until discharge from the geriatric ward, assessed within 72 hours after discharge.)
  • Number of fractures at 3 months after discharge(3 months (90 days) after discharge from the geriatric ward (index hospitalization), assessed at day 90)
  • Number of drug intakes at discharge versus at admission.(At discharge from the index hospitalization (as mentioned in the discharge medication scheme) vs on admission (during the first 72 hours of the index hospitalization))
  • Number of drugs adapted by the treating physician based on recommendations by the clinical pharmacist that are not included in the RASP list.(At discharge from the index hospitalization (as mentioned in the discharge medication scheme), compared to the medication list obtained on admission (this is, during the first 72 hours of the hospitalization))
  • Number of drug intakes at follow-up (1 month and 3 months after discharge)(1 month (30 days) and 3 months (90 days) after the index hospitalization)
  • Number of potentially inappropriate medications on admission, at discharge and at the follow-up moments (1 and 3 months after discharge)(On admission (medication list obtained in the first 72 hours of the admission), at discharge (as mentioned in the discharge medication scheme), 1 (30 days) month after discharge, 3 months (90 days) after discharge)
  • Mortality during admission(During the index hospitalization, from admission to the emergency ward until moment of death on the geriatric ward, assessed up to 72 hours after death.)
  • Number of falls 3 months after discharge(3 months (90 days) after discharge from the geriatric ward (index hospitalization), assessed at day 90)
  • Readmission rate 3 months after discharge(3 months (90 days) after discharge from the geriatric ward (index hospitalization), assessed at day 90)
  • Mortality at 3 months after discharge(3 months (90 days) after discharge from the geriatric ward (index hospitalization), assessed at day 90)
  • Number of drugs at follow-up (1 month and 3 months after discharge)(1 month (30 days) and 3 months (90 days) after the index hospitalization)
  • Number of drugs at discharge versus at admission.(At discharge from the index hospitalization (as mentioned in the discharge medication scheme) vs on admission (during the first 72 hours of the index hospitalization))
  • Difference in number of potentially inappropriate medications identified through the RASP list on admission versus at discharge(At discharge from the index hospitalisation (as mentioned in the discharge medication scheme) versus on admission (medication list obtained in the first 72 hours) of the index hospitalization)
  • Category of drugs adapted by the treating physician based on recommendations by the clinical pharmacist that are not included in the RASP list.(During the course of the index hospitalization, defined as the period between discharge from the geriatric ward and admission to the geriatric department. The outcome parameter will be assessed within 72 hours of discharge.)
  • Category of potentially inappropriate medications identified through the RASP list on admission and at discharge(On admission (medication list obtained in the first 72 hours of the admission), at discharge (as mentioned in the discharge medication scheme))

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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