The use of physiologic assessment and functional SYNTAX score in influencing the treatment strategy for Multi-Vessel Disease (MVD) patients involving intermediate decisions compared to conventional angiography and anatomical SYNTAX score in a real-world scenario

Dr Nattawut Wongpraparut from Faculty of Medicine Siriraj Hospital0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年2月6日

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•1. Age >18 years
•2. Willing to participate and able to understand, read and sign the informed consent document before the planned procedure
•3. Eligible for coronary angiography and/or percutaneous coronary intervention
•4. Stable angina
•5. Recent and stabilized NSTEMI
•Angiographic inclusion criteria
•- Coronary artery disease in two or more native major epicardial vessels or their branches by coronary angiogram with visually assessed de novo coronary stenosis in which one of the lesion has the physiological severity of the lesion is in question (typically 50-90% diameter stenosis)
•- All lesions are amenable to revascularizationÂ

•- Terminal disease with life expectancy of less than 12 months
•- Any patient who at the time of planned angiography has ongoing ischemic symptoms
•- Angiography performed in the context of primary PCI of STEMI
•- Acute coronary syndrome with difficulty in assessing the culprit lesion
•- Pregnancy
•- Severe aortic stenosis
•- Significant valvular heart disease indicated for concomitant valve surgery
•- Cardiogenic shock or hemodynamic instability
•- Contraindication to adenosine
•- Previous CABG
•- Additional investigations planned for the assessment of myocardial viability.
•- Severe asthma
•Angiographic exclusion criteria
•- Heavily calcified or tortuous vessels that in the opinion of the investigator would result in uncrossable of pressure wire

发起方

Dr Nattawut Wongpraparut from Faculty of Medicine Siriraj Hospital