Effects of Upper Extremity Aerobic Exercise Training on Exercise Capacity and Physical Activity Level in Patients With Chronic Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 4
- 主要终点
- Maximal exercise capacity
研究概览
简要总结
Heart failure is a cardiac structural or functional disorder that, despite normal filling pressures, leads to inability to deliver enough oxygen to meet the metabolic needs o tissue. Heart failure is a serious chronic condition that affects a large proportion of the adult population in the world causing high mortality, leading to exercise intolerance and reduced health-related quality of life. Patients included in the cardiac rehabilitation program slow down disease progression, hospitalization decreases, quality of life improves and health expenditures decrease. Despite the frequent use of upper extremities in daily living activities, studies investigating the effect of upper extremity aerobic training on daily living activities, functional exercise capacity and other outcomes are limited. No studies have investigated the effect of upper extremity aerobic exercise training on physical activity level, functional and maximal exercise capacity and other measures in patients with heart failure.
详细描述
It has been reported that exercise capacity in peak arm exercise is almost 30% lower in heart failure patients. For this reason intolerance to arm exercise is a significant problem in heart failure patients and may contribute to a decrease in performance in activities of daily living. Considering the fact that developments in these patients are caused by vasculature functional adaptation the extremity skeletal muscle and applied limbs, upper extremity exercises may be useful to reduce exercise intolerance during activities requiring continuous arm movement.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a diagnosis of chronic heart failure diagnosed at rest below 40% of the left ventricular ejection fraction and class 1-3 according to the New York Heart Association classification
- •Optimal medical treatment at least 30 days and clinically stable
排除标准
- •Patients with unstable angina pectoris
- •Decompensated heart failure
- •Primary pulmonary hypertension
- •Complex ventricular arrhythmia
- •Contraindication to cardiopulmonary exercise testing
- •Patients who have had myocardial ischemia in the past 3 months
- •Ischemic cerebrovascular events
- •Second and third degree atrioventricular block
- •Thrombus detected in the left ventricle
- •Uncontrolled insulin dependent diabetes mellitus
- •Uncontrolled hypertension
- •Renal insufficiency
- •Acute infection
- •Aortic stenosis
- •Acute pulmonary embolism
- •Mental, musculoskeletal, neurological, or systemic illness that will prevent exercise.
结局指标
主要结局
Maximal exercise capacity
时间窗: Second day
It will be evaluated using symptom limited cardiopulmonary exercise testing. The cardiopulmonary exercise test will be performed at a progressively increasing speed and grade
次要结局
- Quality of sleep(Second day)
- Grip strength(First day)
- Physical activity level(First day)
- Fatigue(Second day)
- Anxiety and depression(Second day)
- Quality of life scale(Second day)
- Pulmonary function(First day)
- Respiratory muscle strength(First day)
- Functional exercise capacity(First day)
- Pulmonary muscle endurance(First day)
- Peripheral muscle strength(First day)
- Activity daily of living(Second day)
- Dyspnea(Second day)
- Functional impairment due to dyspnea(First day)
研究者
Meral Boşnak Güçlü
associate professor
Gazi University