"Comparison of safety and efficacy in ultrasound guided supraclavicular and infraclavicular subclavian vein cannulation in ICU patients:A randomized clinical study"

Central vein catheter (CVC) insertion is an essential and routine procedure of modern medicine in critically ill patients in intensive care unit (ICU). CVC catheterization is required for both invasive monitoring as well as therapeutic purposes. USG guided subclavian vein cannulation is associated with lesser numbers of complications as compared to blind landmark technique.The aim of study is to determine the difficulties and advantages of subclavian venous

catheterization using supraclavicular versus and infraclavicular approach under real time ultrasound guidance in ICU patients. Primary objective of this study is to compare the complications during USG guided supraclavicular and infraclavicular subclavian vein cannulation. This prospective, randomized, comparative study will be conducted after approval from the institutional ethical committee. All the patients will be assessed and check-up will done including detail history, general and systemic examination and clinical laboratory tests will be conducted. Patients or their relatives will be explained about the concerned technique and written and informed consent will be obtained.

This hospital based study will be conducted on 80 critically ill patients requiring CVC insertion. Patients who will be admitted to surgical ICU for intensive management whether mechanically ventilated or on spontaneous ventilation of age >18 years will be randomly assigned to two groups of 40 each using computer generated number table. The allocations will be concealed in sequentially numbered, sealed, opaque envelopes.