A Study to Evaluate the Effects of Protein Supplementation in Attenuating the Decline in Performance Following Strenuous Concurrent Exercise
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Isometric Maximal Voluntary Contraction (MVC) Assessment
研究概览
简要总结
This study is designed to investigate whether protein supplementation can improve recovery of muscle function following a strenuous combination of both endurance and resistance exercise. It will specifically investigate the effect of protein supplementation on the recovery of strength, power and endurance exercise performance, along with measures of damage and inflammation of the muscle.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Understanding of the study procedures, restrictions and willingness to participate as evidenced by voluntary informed consent form and has received signed and dated copy of the informed consent form
- •Male participants; age between 18 to 35 years, inclusive
- •Well trained endurance cyclist (competing at a minimum of Category 3 road-racing/estimated 10 mile TT of <23 minutes), with a training history >1 year
- •Good general and mental health
排除标准
- •Currently taking any nutritional supplements, polyphenols or beta-blockers, Non-steroidal anti-inflammatory drugs (NSAIDs), recreational drugs
- •Known or suspected intolerance or hypersensitivity to the study material or any of their stated ingredients
- •Allergy to milk or wheat products
- •Heart or any other medical condition that may contra-indicate participants from taking part in high intensity or exhaustive physical activity
- •Previous participation in this study; another clinical study or receipt of an investigational drug within 30 days of the screening visit; participation in another study involving a protocol to elicit Exercise-Induced Muscle Damage (EIMD) within 6 months of the screening visit
结局指标
主要结局
Isometric Maximal Voluntary Contraction (MVC) Assessment
时间窗: 96 hours (h)
Maximum voluntary isometric contraction (MVIC) will be assessed at the knee during a leg extension movement using an isokinetic dynamometer. MVIC will be used to assess strength. Participants will perform the exercise using the dominant leg at a knee joint angle of 70º three times, with a contraction of 3 seconds (s) on each occasion (each contraction separated by 60 s rest). The peak force (measured in Newton) generated across the three repetitions will be recorded.
Counter Movement Jump (CMJ) Assessment
时间窗: 96 h
Power will be assessed using counter-movement jump. Participants will place their hands on their hips, descend rapidly to \~90º knee joint angle, and then jump as high as possible using a counter-movement. Three jumps will be performed (each jump separated by 60 s rest) and the peak vertical jump height (measured in centimeters) will be recorded.
16.1 Kilometer (km) Cycling Time Trial (TT) Assessment
时间窗: 96 h
The 16.1 km cycling TT assessment will be performed on a cycling ergometer. Participants will be required to complete a distance of 16.1 km in as short a time as possible, while being blinded to time elapsed.
次要结局
- Serum Creatine Kinase Analysis(96 h)
- Serum C-Reactive Protein Analysis(96 h)
- Perceived Muscle Soreness Assessment(96 h)