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临床试验/ISRCTN56462370
ISRCTN56462370已完成未知

Quantification of lipid and leukocyte filtration and the effects on cerebral and renal injury markers and pulmonary function during cardiopulmonary bypass.

Eurosets s.r.l. (Italy)0 个研究点目标入组 50 人开始时间: 2010年9月20日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
50

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Participant is willing and able to give informed consent for participation in the study - any documented history of cognitive impairment will exclude the patient as this may have an effect on biochemical markers of cerebral injury
  • 2. Male or female, aged 18 years or above
  • 3. Patients undergoing elective Coronary Artery Bypass Graft (CABG) surgery
  • 4. Angiographically proven coronary artery stenosis

排除标准

  • 1. Age less than 18 or more than 90 years old
  • 2. Emergency CABG surgery
  • 3. Previous CABG surgery
  • 4. Gross haemodynamic instability:
  • 4.1. Hypertension (systolic blood pressure >160mmHg)
  • 4.2. Hypotension (systolic blood pressure <90mmHg)
  • 4.3. Bradycardia (heart rate <60 beats/min)
  • 5. Diabetes
  • 6. Obesity (BMI >30)
  • 7. Pre-operative heparin regime
  • 8. Abnormal preoperative white cell count (<4 or >10x109 cells/L)
  • 9. Renal failure (serum creatinine >150µmol/L)

研究者

发起方
Eurosets s.r.l. (Italy)

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