A randomized controlled study of lung protective ventilation and conventional ventilation in patients undergoing abdominal laparoscopic surgeries under general anesthesia at SMS Medical College, Jaipur
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 188
- 试验地点
- 1
- 主要终点
- To assess and compare intraoperative Pulmonary Oxygenation in both groups by calculating ratio of Partial pressure of oxygenation in arterial blood (PaO2) to the fraction of inspiratory oxygen concentration (FiO2), PaO2 (mmHg), PaCO2 (mmHg), PH values intraoperatively by Arteiral Blood Gas analysis
研究概览
简要总结
This prospective, randomized comparative study is being conducted at SMS Medical College and Hospital, Jaipur, to evaluate the effects of lung protective ventilation (LPV) versus conventional ventilation (CV) strategies on pulmonary function in patients undergoing elective abdominal laparoscopic surgery under general anesthesia. A total of 188 patients will be enrolled and randomized into two equal groups (LPV and CV). Parameters such as arterial blood gas values, ventilatory mechanics, and intraoperative hemodynamic changes will be recorded at predefined time intervals. The aim is to assess whether LPV improves intraoperative pulmonary outcomes without adverse hemodynamic effects, thereby supporting safer anesthetic practices in laparoscopic procedures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing to give written informed consent.
- •2.Patients 18-60 years planned for laparoscopic surgeries.
- •3.American Society of Anaesthesiologists (ASA) grade I and II.
排除标准
- •Patient should not be part of any other study.
- •Pateints with the need to continue prolonged mechanical ventilation after surgery.
- •Patients with abnormal spirometry.
结局指标
主要结局
To assess and compare intraoperative Pulmonary Oxygenation in both groups by calculating ratio of Partial pressure of oxygenation in arterial blood (PaO2) to the fraction of inspiratory oxygen concentration (FiO2), PaO2 (mmHg), PaCO2 (mmHg), PH values intraoperatively by Arteiral Blood Gas analysis
时间窗: After induction , 30 min after pneumoperitoneum and then at the end of surgery
次要结局
- To assess and compare change in Hemodynamics parameters in both groups.(After induction, 15min,)
- To assess and compare lung mechanics in both groups(After induction, 15min,)
研究者
Dr Indu Verma
Sawai Man Singh Medical College and Hospitals