Effect of Expiratory Muscle Strength on Hospital Admission, Disease Severity and Quality of Life in Patients With Bronchiectasis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Respiratory Muscle Strength
研究概览
简要总结
This study investigates the relationship between expiratory muscle strength and clinical outcomes such as disease severity, hospital admissions, and quality of life in individuals with bronchiectasis.
详细描述
This study aims to examine the relationship between expiratory muscle strength and clinical outcomes such as disease severity, hospital admission history, and quality of life in individuals with bronchiectasis. Effective coughing is a critical physiological reflex for airway clearance; however, the relationship between expiratory muscle strength and cough effectiveness in the bronchiectasis population has not been clearly established. Identifying expiratory muscle weakness as a potential contributor to increased symptom burden and impaired airway clearance may improve clinical understanding and support the development of targeted physiotherapy interventions. The findings of this study could serve as a foundation for future interventional research in pulmonary rehabilitation and respiratory muscle training for this population.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Having a diagnosis of non-cystic fibrosis bronchiectasis
- •Without an acute infection at the time of assessment (confirmed by medical history, serum C-reactive protein levels, chest X-ray and/or HRCT).
- •Being between 18 and 65 years of age
排除标准
- •Myopathies
- •Stroke (Cerebrovascular accident - CVA)
- •Pregnancy
- •Unstable cardiac disease
结局指标
主要结局
Respiratory Muscle Strength
时间窗: Baseline
Respiratory muscle function will be assessed by measuring maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) in the sitting position using a mouth pressure device (MEC PFT Systems Pocket-Spiro).
次要结局
- Modified Medical Research Council Dyspnea Score(Baseline)
- Leicester Cough Questionnaire(Baseline)
- Bronchiectasis Severity Index(Baseline)
- Hospital Anxiety Depression Scale(Baseline)
- Fatigue severity scale(Baseline)
- Spirometric measurements (Forced vital capacity)(Baseline)
- Spirometric measurements (First second forced expiratory volume)(Baseline)
- Spirometric measurements (FEV1/FVC ratio)(Baseline)
研究者
Nisanur Tutuş
Principal Investigator
Saglik Bilimleri Universitesi