NL-OMON23265尚未招募不适用
Preservation and Transfer of Hepatitis B Virus Immunity after Non-Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation in Adult Sickle Cell Disease Patients.
Amsterdam UMC0 个研究点目标入组 24 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 24
研究概览
简要总结
暂无简介。
入排标准
入选标准
- •In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- •- Age 18 or older
- •- High performance liquid chromatography (HPLC) confirmed diagnosis of SCD (not applicable to participating donors).
- •- An indication for and a planned matched sibling or haploidentical donor non-myeloablative HSCT at the Amsterdam UMC, location AMC (not applicable to patients in cohort 2 (control group) and participating donors)
- •- Written informed consent
排除标准
- •A potential subject who meets any of the following criteria will be excluded from participation in this study:
- •- History of either cleared, chronic or active HBV infection (positive HBsAg, anti-HBs, anti-HBc and/or HBV DNA)
- •- History of auto-immune diseases and/or use of immunosuppressive drugs
- •- History of HIV infection
- •- Known hypersensitivity to yeast of any vaccine constituent
- •- Donor with a history of HBV infection
研究者
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Preservation and Transfer of Hepatitis B Virus Immunity after Non-Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation in Adult Sickle Cell Disease Patients (Protect Study).Sickle cell diseaseNL-OMON52342Academisch Medisch Centrum42
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