Comparing Intermittent Fasting, Clean Ketogenic Diet, and Their Combined Effects on Body Composition, Cardiometabolic Markers, and Metabolic Health
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 79
- 试验地点
- 1
- 主要终点
- Concentration of HDL Cholesterol
研究概览
简要总结
A cross-study analysis combined data from two sequential pre-post intervention studies conducted at the University of Tennessee at Martin, yielding a three-arm design comprising intermittent fasting alone (n = 16), clean ketogenic diet alone (n = 22), and combined clean ketogenic diet with intermittent fasting (n = 41). The clean ketogenic diet restricted carbohydrate intake to 20 grams per day from whole unprocessed sources and eliminated refined sugars, high-fructose corn syrup, and ultra-processed foods.
详细描述
The intermittent fasting protocol employed a 16:8 time-restricted eating window. Paired-samples t-tests examined within-group pre-to-post changes. One-way analyses of variance with Tukey post-hoc comparisons examined between-group differences in magnitude of change. Effect sizes are reported as Hedges' g for within-group comparisons and eta-squared for between-group comparisons. An independent samples t-test compared glycosylated hemoglobin changes between the intermittent fasting and combined groups. Spearman and Kendall correlations examined associations between fat mass and cardiometabolic change.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
盲法说明
it was a blind study for the researcher who was analyzing the data
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Clean ketogenic Diet
Participants ate low carb, under 20 g per day
干预措施: Diet (Other)
Intermittent fasting
Participants went on a 16:8 feeding window
干预措施: Diet (Other)
Clean keto and IF
Combined Clean keto and intermittent fasting
干预措施: Diet (Other)
结局指标
主要结局
Concentration of HDL Cholesterol
时间窗: Baseline and 30 days
Fasting Blood draw to assess high-density lipoprotein cholesterol levels
Concentration of Serum Triglycerides
时间窗: baseline and 30-days
Fasting blood draw to assess serum triglyceride levels
Concentration of Hemoglobin A1c (HbA1c)
时间窗: Baseline and 30 days
Blood draw to assess HbA1c as a marker of glycemic control
次要结局
未报告次要终点
研究者
Angie MacKewn
Professor
The University of Tennessee at Martin