PROPHYLACTIC INTRAVENOUS KETAMINE, ONDANSETRON AND PETHIDINE IN PREVENTING PERIOPERATIVE SHIVERING IN PATIENTS UNDERGOING ELECTIVE KNEE REPLACEMENT SURGERY UNDER SPINAL ANAESTHESIA: A RANDOMIZED PARALLEL-GROUP, PLACEBO CONTROLLED COMPARATIVE STUDY.

Army Hospital R&R Delhi India0 个研究点目标入组 216 人开始时间: 2020年11月2日最近更新: 2024年8月19日

适应症

试验速览

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•American Society of Anesthesiologists (ASA) physical status I or II], aged (18-75 years), scheduled for Total Knee Replacement surgical operations under spinal anesthesia

•2.Exclusion Criteria included patient refusal, ASA Grade > 2, Contraindications to spinal anesthesia, bleeding disorder, thyroid disease, Addison’s disease, Parkinson’s disease, Raynaud’s syndrome. History of convulsions/epilepsy, bronchial asthma, allergy to the agents to be used, blood transfusion during surgery, initial axillary temperature <36.0 or >37.5 °C , use of sedative-hypnotic agents, vasodilators, antidepressants therapy with selective serotonin reuptake inhibitors and monoamine oxidase inhibitors, benzodiazepines. or patients having inadequate Sub arachnoid blockade requiring supplementation by general anaesthesia

发起方

Army Hospital R&R Delhi India