Impact of Exercise Therapy on Functional Capacity in Patients Listed for Liver Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Number of participants with intervention-related adverse events as assessed by CTCAE v4.0
研究概览
简要总结
A UK prospective, single-centre feasibility study investigating the effects of exercise therapy on functional capacity in patients on the waiting list for liver transplantation. Patients will receive a 12-week home prehabilitation program (daily step program; functional resistance exercise sessions; telephone health call or virtual clinic). The following will be assessed at weeks 0, 6 and 12 weeks: feasibility (recruitment, compliance, safety, patients perception), functional capacity (ISWT, SPBT), psychological wellbeing (HADS questionnaire) and quality of life (EQ-5D)
详细描述
as above
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meet the United Kingdom Liver Transplant criteria for listing
- •Accepted on the liver transplant waiting list for a primary transplant
- •Adults ≥18years who have an indication for a liver transplant
- •Diagnosed with sarcopenia at liver transplant assessment
排除标准
- •Significant cardiovascular instability including a recent Myocardial infarction, recent Cerebrovascular accident and/or a recent unstable arrhythmia
- •Unstable encephalopathy - open to interpretation by the chief investigator
- •Patient or next of kin non-English speaking
- •Inpatients
- •Refusal or lacks capacity to give informed consent
结局指标
主要结局
Number of participants with intervention-related adverse events as assessed by CTCAE v4.0
时间窗: 12-week
As this is a feasibility/Pilot study the investigators need to assess if any participants have any adverse events related to the home prehabilitation programme and if so, determine the severity and frequency
次要结局
未报告次要终点
研究者
Matthew Armstrong
Principal investigator, Specialist Registrar in Hepatology and Honorary Clinical Fellow
University of Birmingham