Acute Effects of the 3/7 Method and 3X9 Method in Resistance Training on Testosterone, Glucocorticoid Cortisol, Growth Hormone and Lactate in Heart Failure and Coronary Artery Disease During Cardiac Rehabilitation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- change in Testosterone
研究概览
简要总结
The study proposes to measure the effect of resitance training (RT) (3/7 method) on biological markers of muscle hypertrophy in a cardiac population.
3/7 method consisting of five sets of an increasing number of repetitions (3 to 7) during successive sets and brief inter-set intervals (15 s). This method is compare to 3X9 method, 3 series of 9 repetitions with inter-set (1min).The training exercise consisted of contraction on machine (leg press, triceps press, leg curl, traction, leg extension) with load of ~ 70% of one repetition maximal (1RM).
Before these trainings all subject perform HIIT on bicycles (2 min high intensity (80% Wmax) and 2 min low intensity (50% Wmax) during 30 minutes.
The investigators collect blood sample before exercice, after HIIT and after RT.
It is randomized cross-over study.
详细描述
The subjects come on two different days minimum 2 days and maximum 10 days between the two tests. They were instructed to avoid exercise the day before they participated in the study.
The investigators collect blood 2 minutes after endurance training (HIIT) and 2 min after RT training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Clinical Coronary artery diseases
- •Heart failure with reduced ejection fraction
排除标准
- •acutely decompensated heart failure
- •electrocardiographic evidence of ischemia
- •significant valvular disease
- •orthopedic/neurologic disorders that limited exercise
结局指标
主要结局
change in Testosterone
时间窗: within 2 minutes after TR training session on day 1
nmol/l
change in ph
时间窗: within 2 minutes after TR training session on day 1
venoust
Change in Lactate
时间窗: within 2 minutes after TR training session on day 1
mmol/l
change PCO2 venoust
时间窗: within 2 minutes after TR training session on day 1
mm Hg
change Glucocorticoid Cortisol
时间窗: within 2 minutes after TR training session on day 1
nmol/l
change in Growth Hormone
时间窗: within 2 minutes after TR training session on day 1
ng/ml
次要结局
- Pleasure of the session scale(within 4 minutes after TR training session on day 1)
- Borg scale(within 4 minutes after TR training session on day 1)
研究者
Alexis Gillet
Principal Investigator
Université Libre de Bruxelles