Comparison of 2 Hyperglycemia-correction Scales in Hospitalized Patients in an Institution in Bogotá, Colombia
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 116
- 主要终点
- Number of paticipants with Glicemic control
研究概览
简要总结
Hyperglycemia in the hospital is associated with multiple adverse outcomes. Previously, the mobile insulin scheme was used for its control. However, in the last decade, several studies have shown that the insulin basal-bolus (basal plus) regimen is associated with better glycemic control and a lower risk of hypoglycemia.
详细描述
Introduction:
Hyperglycemia in the hospital is associated with multiple adverse outcomes. Previously, the mobile insulin scheme was used for its control. However, in the last decade, several studies have shown that the insulin basal-bolus (basal plus) regimen is associated with better glycemic control and a lower risk of hypoglycemia.
Objective:
To compare the sensitive scheme of Umpierrez and the correction factor suggested by Davidson (1700/total dose of insulin) for the correction of hyperglycemia in patients with type 1 diabetes mellitus.
Methods:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with diabetes mellitus who presented hyperglycemia (above 140 mg/dl) located in the general ward, emergency room or hospitalization and who received a basal or basal bolus insulin scheme.
排除标准
- •pregnancy, with acute decompensation of diabetes (diabetic ketoacidosis-hyperosmolar state) or type 1 diabetes
研究组 & 干预措施
Davidson
Davidson correction factor
干预措施: insulin (Drug)
Umpierrez
The Umpierrez sensitive correction scheme correction
干预措施: insulin (Drug)
结局指标
主要结局
Number of paticipants with Glicemic control
时间窗: 5 hours
Glycemic control defined as glucose levels between 70 and 180 mg/dl measured with a glucometer
次要结局
- Number of participants with hypoglycemia(6 hours)
研究者
Javier Mauricio Mora Mendez
Principal investigator, cinical professor in internal medicine
Hospital Universitario Clinica San Rafael