Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis Collection
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 3,500
- 试验地点
- 77
- 主要终点
- Blood Samples
研究概览
简要总结
Numerous neurological disorders affecting the central and peripheral nervous system can be attributed to the immune system through multiple effector mechanisms. However, current treatments could be drastically improved by faster and more accurate diagnosis. The sample collection will benefit to patients with rare neuroimmune syndromes such as Autoimmune Encephalitis (AE) and Paraneoplastic Neurological Syndromes (PNS) leading to a better and early diagnosis, as well as treatment improvement.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with consent
- •Patient with well-characterized antibodies in serum or cerebrospinal fluid or not
- •Patient with neurological disorder compatible with PNS or auto-immune encephalitis
排除标准
- •Refusal of consent
- •Patient under guardianship
研究组 & 干预措施
Paraneoplastic neurological syndrome patients and autoimmune encephalitis patient
patients with diagnosis of paraneoplastic neurological syndrome or autoimmune encephalitis
干预措施: Collection of biological sample with sera, CSF, buffy coat, PBMC, plasma. (Biological)
结局指标
主要结局
Blood Samples
时间窗: 10 years
Assessment of biocollection of blood samples
Cerebrospinal fluid biocollection
时间窗: 10 years
Assessment of biocollection of Cerebrospinal fluid
次要结局
- Scientific collaboration(10 years)
- Scientific(10 years)