A Comparative Clinical Study Of Keshamasi Eye Ointment And CMC Eye Ointment On Shushkakshipaka w.s.r To Dry Eye Disease
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Reduced following symptoms
研究概览
简要总结
Acharya Sushrut who described Shalakyatantra in Sushrut Samhita Uttartantra has described 17 sarvagat rogas and vagbhat has described 16 sarvagat rogas .Shushakakshipaka is mentioned in the classical literature of Ayurveda under sarvagata netrarogas.Shushkakshipaka is characterized by kunita daruna ruksha vartma aavila darshanam sudarunapratibodhana toda bheda and daha.Dosha is vaat dushya is rakta.It is correlated with Dry Eye Disease.It is a multifactorial disease characterized by loss of homeostatsis of the tear film and accompanied by ocular symptoms in which the tear film instability hyperosmolarity and neurosensory abnormalities.It is classified into two stages aqueous tear deficient dry eye and evaporative dry eye.Now a days it is increased because of all lifestyle changes reduced quality of life and increased stress and hormonal changes.In Ayurveda there are various kriyakalpas but now a days it is not feasible for the patients.So there is a need of advance procedure like eye ointment which is affordable easy to handle and patient friendly.which acts locally for enhancing the management of DED.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient is willing and able to participate in the study.
- •Patient presenting with signs and symptoms of Dry Eye Disease ,itching etc and lakshana of Shushkakshipaka like gharsha ,vishushkatwa , kandu , daha etc
- •Patients having mild dryness(14 to 10 mm of Schirmer test)and moderate dryness(10 to 6mm of schirmer test).
排除标准
- •1.Age group less than 18 years and more than 50 years
- •Patient is not willing to participate in this study
- •Allergic and inflammatory conditions of eye Ex. Acute Conjunctivitis etc 4.Patients having severe dryness in eyes( less than and equal to 5mm schirmer test) 5.Severe cases of Dry Eye Disease with complications like corneal ulcer ,uveitis ,glaucoma etc 6.Dry eye associated with sjogrens syndrome 7.Patients with known case of HTN ,Thyroid ,DM, Arthritis.
结局指标
主要结局
Reduced following symptoms
时间窗: 3 Months
Gharsha (foreign body sensation)
时间窗: 3 Months
Vishushkatwa (dryness)
时间窗: 3 Months
Kandu(itching)
时间窗: 3 Months
Daha (burning sensation)
时间窗: 3 Months
kunita vartma(sticky eyelids)
时间窗: 3 Months
Upadeha (Heaviness of eyes)
时间窗: 3 Months
次要结局
- Recurrence of symptoms of Dry Eye Disease(3 Months)
研究者
DRSAMRADNI JAGDISH GALINDE
Dr DY Patil School Of Ayurveda Deemed To Be University Nerul Navi Mumbai 400706