The Impact of Varying Exercise Training Intensity on Clinical Asthma Outcomes and Inflammation in Adults with Asthma: A Randomised Controlled Trial

Hunter Medical Research Institute0 个研究点目标入组 46 人开始时间: 2017年7月10日最近更新: 2021年6月28日

适应症

试验速览

暂无简介。

•1. Physician diagnosed asthma
•2. Able to provide written informed consent
•4. Body mass index (BMI) <=40kg/m2 (due to increased risk of exercise-related complication in those with a BMI >40kg/m2)
•5. Not a current smoker (never smoker or quit at least 6 months ago)
•6. Post-bronchodilator forced expiratory volume in 1 second (FEV1) >=50% predicted.
•7. Deemed suitable for vigorous-intensity exercise by the study coordinator, according to the ESSA Adult Pre-Exercise Screening Tool”.

•1. Asthma is not the primary respiratory diagnosis
•2. A moderate exacerbation (oral corticosteroid or antibiotic use) in the past four weeks or
•severe exacerbation (hospitalisation) in the past three months
•3. Participation in a moderate- or vigorous-intensity exercise session within 2 days of the
•scheduled study visits.
•4. Known cardiac condition contraindicated for exercise
•5. Musculoskeletal contraindication to exercise
•6. Uncontrolled hypertension (blood pressure >180/100mmHg)
•8. Diabetes mellitus
•9. Taking cholesterol lowering medication
•10. Pregnancy or breastfeeding
•11. Resting SpO2 <=95% on room air
•12. Participation in an interventional research study in the last four weeks
•13. Currently exercising at a moderate-intensity or greater for >90 mins/week
•14. Subject has a clinically important medical illness (including serious psychological
•disorders) likely to interfere with management or participation in the study

发起方