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临床试验/NCT03903328
NCT03903328已完成不适用

A Preliminary Study of Prevalence of Sarcopenia Among Elderly Living in Care Facilities in Klang Valley, Malaysia

Universiti Tunku Abdul Rahman0 个研究点目标入组 205 人开始时间: 2016年12月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
205
主要终点
Gait speed

研究概览

简要总结

The primary aim of this study was to investigate the prevalence of age-related progressive decline in muscle mass and strength (Sarcopenia) among Malaysian elderly residing in long-term care facilities. It is a very important condition to study as it is associated with high incidence of fall, hospitalization and mortality.

详细描述

Over the past few decades, one condition that prominently affects the muscular system, known as sarcopenia, has captured the attention of healthcare experts and researchers. Sarcopenia is a geriatric syndrome characterized by the involuntary, gradual and generalized deterioration of skeletal muscle mass and strength with advancing age. It is to be noted that while sarcopenia is predominantly a syndrome of the elderly, its development may also be observed in various conditions such as disuse, malnutrition and cachexia, all of which are not exclusive only to the elderly. As of now, there are still ongoing research on an international scale with regards to its epidemiology, risk factors, causative factors, adverse clinical complications, prevention and treatment.

Beginning in 1st of October, 2016, Centres for Disease Control and Prevention (CDC) has finally officialised an International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10- CM) code for sarcopenia after its final proposal since April 2015. This establishment has enabled comprehensible clinical guidelines for diagnosis and treatment of sarcopenia, as well as separate reporting and data collection for sarcopenia in the medical community.

In essence, sarcopenia appears to be one of the most important causes of functional impairment, physical disability and loss of independence in older adults and a prevalence study will help to estimate the deleterious effects of this condition on the elderly living in the care facility, who happen to be the less privileged group as compared to their counterparts dwelling in the community.

研究设计

研究类型
Observational
观察模型
Ecologic Or Community
时间视角
Cross Sectional

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Currently residing in a long-term care facility
  • Ability to walk, with or without the use of any walking aid
  • Citizen of Malaysia

排除标准

  • Inability to stand for height, weight and gait speed assessments
  • Presence of cardiac pacemaker
  • Presence of artificial limbs / prosthesis / metal implants
  • Difficult or dangerous behaviours
  • Severe cardiac, pulmonary, or musculoskeletal disorders
  • Severe cognitive impairment or any disability that makes communication impossible
  • Presence of terminal illness
  • Co-morbidities associated with high risk of falls (e.g. Parkinson's disease or CVA) or that may directly influence affect gait speed

结局指标

主要结局

Gait speed

时间窗: less the 10 minutes on an average

Usual gait speed was used as a measure of physical performance, where the subject was required to walk along a 5 meter straight path. Time recorded using a stopwatch and speed recorded in meters per second

Grip strength

时间窗: 1 minute to 10 minutes

Measurement of muscle strength was done using a Jamar hydraulic handheld dynamometer, only one maximal effort was allowed. However, for erroneous performance another attempt was provided after 10 minutes of rest. The measure was recorded in Kgf.

Skeletal muscle mass

时间窗: 10 minutes

The skeletal muscle mass was measured using a Research grade Segmental BioImpedance Analyser to help derive the skeletal muscle mass index (Appendicular skeletal muscle mass/square of height= kg/m2)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Pramod Divakara Shenoy, MPT

Head of Department of Physiotherapy and Senior Lecturer

Universiti Tunku Abdul Rahman

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