Correlation of Sarcopenia and Peripheral Artery Disease With Chronic Limb Threatening Ischemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 97
- 试验地点
- 1
- 主要终点
- psoas muscle area (PMA) [measured by computed tomography (CT)]
研究概览
简要总结
To evaluate the correlation of Sarcopenia Parameters and Peripheral Artery Disease with chronic limb threatening ischaemia.
详细描述
Prior researches indicated a relatively high prevalence of sarcopenia among patients of Peripheral Artery Disease. However, the relationship between sarcopenia and progression of Peripheral Artery Disease with chronic limb threatening ischaemia remained poorly understood. Thus, this cohort study aimed to evaluate the correlation of Sarcopenia Parameters, such as psoas muscle area (PMA) and total abdominal muscle area (TAMA) at the L3 vertebral level, measured by computed tomography (CT), and progression of Peripheral Artery Disease with chronic limb threatening ischaemia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients of Peripheral Artery Disease, including intermittent claudication and Chronic Limb Threatening Ischemia;
- •Patients with Rutherford grade 2-6 between Jan.1 2023 and Dec.31 2024;
- •Patients at age 18-80;
- •Patients underwent an in-hospital routine enhanced whole abdomen to lower extremities CT scan;
- •Patients able to complete the clinical follow-up for 3 months.
排除标准
- •Poor CT quality or incomplete images;
- •Incomplete clinical data;
- •In-hospital mortality during Jan.1 2023 and Dec.31 2024.
结局指标
主要结局
psoas muscle area (PMA) [measured by computed tomography (CT)]
时间窗: 2023.1.1~2024.12.31
psoas muscle area (PMA) (square centimeters) was regarded as a kind of typical sarcopenia parameters, measured by computed tomography (CT) at the L3 vertebral level
total abdominal muscle area (TAMA) measured by computed tomography (CT)
时间窗: 2023.1.1~2024.12.31
total abdominal muscle area (TAMA) (square centimeters) was regarded as a kind of typical sarcopenia parameters, measured by computed tomography (CT) at the L3 vertebral level
次要结局
未报告次要终点
研究者
Zhijun Bao
Hospital director
Fudan University
