Design, Implementation and Analysis of a Penicillin Allergy Delabeling Model in Hospitalized Patients
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 165
- 试验地点
- 2
- 主要终点
- Proportion of patients hospitalized in which the penicillin allergy label is removed
研究概览
简要总结
Design, implementation and analysis of an allergy assessment and management model beta-lactams in hospitalized patients
详细描述
To evaluate the impact of a healthcare process for risk stratification based on the clinical history and the application of a structured questionnaire, on the Proportion of hospitalized patients in whom the penicillin allergy label is removed
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Ability to understand the study after reading the patient information sheet (Appendix II) and providing signed consent for participation (Appendix III: informed consent form).
- •Patients with a reported allergy to penicillin and/or cephalosporins that has not been investigated or with inconclusive prior testing.
排除标准
- 未提供
研究组 & 干预措施
Patients with an active allergy label for beta-lactams admitted to hospital
Clinical evaluation involving a review of the patient's history and a structured questionnaire, allows stratification of allergy risk into 3 categories, and managed accordingly. 1) Tipus A) Patients with a non-immune-mediated adverse reaction or with posterior tolerance. 2) Grup B) Patients with low risk potentiallly immune-mediated mechanism are considered candidates for exposure and re-exposure to penicillin and/or cephalosporins, as clinically indicted.
3) Grup C) Patients with a previous adverse reaction considered high-risk Type C, IgE-mediated or non-immediate Type II-IV reactions,
干预措施: Pragmatic allergy management according to risk stratification (Other)
结局指标
主要结局
Proportion of patients hospitalized in which the penicillin allergy label is removed
时间窗: At enrollment time
Proportion of patients hospitalized in which the penicillin allergy label is removed
次要结局
未报告次要终点