Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 69
- 试验地点
- 1
- 主要终点
- The relationship between brain structure, heart rate variability and fatty acid of the irritable bowel syndrome patients.
研究概览
简要总结
This study is to analyze the relationship between brain structure, the heart rate variability and the serum fatty acid component of the irritable bowel syndrome patients.
详细描述
Several studies showed that the gray matter and white matter of the brain related to the symptoms of irritable bowel syndrome patients.
The investigators study is to analyse the relationship between thickness of cortex of irritable patients, the sympathetic tone and the serum fatty acid component of the irritable bowel syndrome patients. It is to clarify the mechanism of irritable bowel syndrome, whether the symptoms of irritable bowel syndrome are related to the thickness of cortex or inflammation status of the body.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •between 20 and 50 years old
- •meet Rome III criteria
排除标准
- •colon and small intestinal disease
- •psychiatric disease patients
- •patients received major surgery in the past 5 years
- •diabetic patients
- •patients with metal implant
结局指标
主要结局
The relationship between brain structure, heart rate variability and fatty acid of the irritable bowel syndrome patients.
时间窗: Patients who suffered from IBS for more than 5 years.
次要结局
- The relationship between thickness of brain cortex and the symptoms of irritable bowel syndrome(Patients who suffered from IBS for more than 5 years.)