Impact of Neo adjuvant chemotherapy on surgical decision and peri-operative outcome in patients with very advanced buccal cancers - nil

AIIMS, New Delhi0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年7月22日

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•. All patients age 18 years and above with the confirmed diagnosis of locally advanced non metastatic carcinoma- buccal mucosa who were deemed as borderline resectable on multi-disciplinary team discussion and received neo-adjuvant chemotherapy before definitive surgery from January 1 , 2019 to Feb 2023 at both the centres( retrospective study) .
•2. For prospective part of study, all newly diagnosed locally advanced- non metastatic carcinoma buccal mucosa patients who will be fulfilling below mentioned criteria for borderline resectability will be included.
•a. Gingivo- buccal complex cancers with extensive skin involvement.
•b. Skin edema reaching upto the level of zygoma.
•c. Lateral pterygoid muscle, temporalis insertion or retroantral fat involvement.
•3. Performance status: 0-1
•4. Medically fit for definitive surgery

•All patients with disease extension to infra-notch area and pterygo-maxillary fissure involvement will not be included in the study.

发起方

AIIMS, New Delhi