The Power Couple of Regional Analgesia? A Prospective Randomized Controlled Trial Comparing Block Duration With Liposomal Bupivacaine and Dexamethasone

Duke University0 个研究点目标入组 80 人开始时间: 2026年8月1日最近更新: 2026年6月3日

试验速览

阶段: 4 期
状态: 尚未招募
发起方
入组人数: 80

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

This prospective randomized clinical trial evaluates the duration of sensory blockade in patients undergoing shoulder surgery receiving interscalene brachial plexus blocks with either liposomal bupivacaine alone or liposomal bupivacaine combined with dexamethasone.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Triple (Care Provider, Investigator, Outcomes Assessor)

盲法说明

Provider given care is not preparing study drug

入排标准

年龄范围: 18 Years 至 80 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Adults aged 18 to 80 years
•ASA physical status 1-3
•Undergoing primary shoulder surgery with interscalene nerve block

排除标准

•Revision shoulder surgery
•Daily chronic opioid use (over 3 months of continuous opioid use)
•Inability to communicate pain scores or need for analgesia
•Infection at the site of block placement
•Age under 18 years old or greater than 80 years old
•Pregnant women (as determined by point-of-care serum bHCG)
•Intolerance/allergy to local anesthetics
•Weight <50 kg
•severe pulmonary disease including chronic obstructive pulmonary disease and restrictive lung disease
•Suspected, or known addiction to or abuse of illicit drug(s), prescription medicine(s), or alcohol within the past 2 years.
•Uncontrolled anxiety, schizophrenia, or other psychiatric disorder that, in the opinion of the investigator, may interfere with study assessments or compliance.
•Current or historical evidence of any clinically significant disease or condition that, in the opinion of the investigator, may increase the risk of surgery or complicate the subject's postoperative course.

研究者

发起方

Duke University

申办方类型

Other

责任方

Sponsor

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