Virtual Left Ventricular Lead Navigation in Patients With Ischemic Cardiomyopathy
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- dP/dt measurements observed during pacing from different left ventricular regions
研究概览
简要总结
Presently, the left ventricular lead is placed in a similar position for all patients. It is not known whether placing this lead in different positions in the heart will make the heart pump better. In this study, the investigator will collect measurements of the heart's electrical activity during an Electrophysiology Study (EP study or EPS). The hope is that these measurements will provide the know how to develop an individualized left ventricular lead placement "prescription" for patients referred for left ventricular lead pacing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ischemic cardiomyopathy
- •Intrinsic QRS duration >120 milliseconds
- •LV ejection fraction <40%
排除标准
- •Persistent atrial tachyarrhythmia
- •Active cardiac ischemia
- •Cerebrovascular accident within 6 months
- •Surgical or percutaneous cardiac revascularization procedure within 3 months
- •Under 18 years of age
- •Participating in a clinical study that would preclude enrollment
- •Unable to provide informed consent
研究组 & 干预措施
Electrophysiology Study
This is a single arm study, all study participants will be referred for an Electrophysiology Study
干预措施: Collection of measurements during LV pacing during electrophysiology study (Other)
结局指标
主要结局
dP/dt measurements observed during pacing from different left ventricular regions
时间窗: Measurements will be observed at the time of the electrophysiology study (EPS) at enrollment.
During the electrophysiology study, the dP/dt measurements will be observed during pacing from different left ventricular regions.
次要结局
未报告次要终点
研究者
David Schwartzman
Professor of Medicine, Cardiac Electrophysiology, University of Pittsburgh
University of Pittsburgh