The Impact of Fish Oil Supplementation on the Outcome of Children with Pneumonia in the Intensive Care Unit
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 122
- 试验地点
- 1
- 主要终点
- Hospital length stay
研究概览
简要总结
The aim of study is to investigate the effect of enteral feeding of Omega-3 on the outcome of children with Pneumonia in PICU
详细描述
Group A(cases) will be supplemented by omega-3 fatty acids for immediate post admission consecutive 7 days besides conventional treatment of pneumonia, in a dose of 350 mg twice daily for children less than 3 years and 450 mg twice daily for older children according to the standard treatment per the American Institute of Medicine of the National Academies guidelines for maximum dose for this age group. (Institute of Medicine of the National Academies,2016)
Side effects of omega-3 supplements are usually mild. They include unpleasant taste, bad breath, bad-smelling sweat, headache, and gastrointestinal symptoms such as heartburn, nausea, and diarrhea. (Office of Dietary Supplements ,2016)
Group B(controls) will be received enteral feeding without omega-3 fatty acid support.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 1 Month 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All children patients with severe pneumonia admitted to PICU
- •Both sexes
- •Age: under 5 years
- •Whose parents or caregivers approve for participation in the study
排除标准
- •Patients with chronic illnesses to exclude bias that could be emerged due to the chronic disease effect
- •Whose parents or caregivers will not apply for participation in the study
- •Patients who will be contraindicated for enteral feeding
研究组 & 干预措施
Children with Pneumonia in intensive care unit receiving fish oil and the standard treatment
干预措施: Fish oil (Omega) (Dietary Supplement)
Children with Pneumonia in intensive care unit receiving the standard treatment only
结局指标
主要结局
Hospital length stay
时间窗: Through study completion, an average of 1 yea
Hospital length stay will be measured between the two groups
次要结局
未报告次要终点
研究者
Hoda Atef Abdelsattar Ibrahim
Dr
Cairo University