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临床试验/NCT05402683
NCT05402683Unknown不适用

Ultrasound Versus Clinical Tests as Predictors of Difficult Endotracheal Intubation in Patients With Obstructive Sleep Apnoea Undergoing Elective Surgery Under General Anaesthesia

Tanta University1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2022年2月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
70
试验地点
1
主要终点
ultrasound parameters

研究概览

简要总结

Obstructive sleep apnoea (OSA) is the most serious kind of the sleep-disordered breathing group, characterised by recurrent episodes of partial to complete obstruction of the upper airway resulting in inefficient alveolar gas exchange and desaturation[1].

It is a commonly encountered condition with a reported prevalence of 9-25% in the general population [2].

However, the majority of OSA patients presenting for surgery remain undiagnosed or untreated[3], contributing to a high rate of unexpected adverse airway outcome[4].

The various airway abnormalities represented by OSA include a large tongue, collapsible airway and crowding of the oropharyngeal structures, among others[5].

Accurate airway assessment should always be performed so as to provide appropriate planning and management of expected difficult intubation, but the common clinical screening tests (Mallampati score, inter-incisor distance, mento-hyoid distance, BMI, etc ) have shown low sensitivity and specificity with a limited predictive value, especially if only a single assessment method is used[6].

Ultrasonography could be a highly sensitive and specific tool for prediction of difficult intubation in OSA patients presented for elective surgery by measuring tongue base thickness, distance between lingual arteries, hyo-mental distance and condylar mobility.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
21 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 21-60 years old
  • ASA I, II, or III
  • STOP-BANG scoring >3

排除标准

  • Age <21 years old 2) patients with cervical spine injury, limited neck mobility, neck swelling 3) patients with lost incisor teeth 4) asymmetric mobility of the temporomandibular joint as in maxillofacial injuries/malignancies prior to surgery on the airway 5) pregnancy

结局指标

主要结局

ultrasound parameters

时间窗: preoperative assessment

evaluate the accuracy of the ultrasound parameters as predictors of difficult intubation in OSA patients in the perioperative period.

次要结局

  • which is better(preoperative assessment)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amer Bahir Soliman

Amer Soliman

Tanta University

研究点 (1)

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