Assessment of Body Composition and Physical Function in Older Adults With Obesity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Fat Mass
研究概览
简要总结
Sarcopenia, which is the loss of muscle mass and strength or physical function, naturally occurs in aging. In sarcopenic obesity, growth of muscle mass and increments in strength do not parallel weight gain, and places older adults at increased risk of falls, fractures, physical disability, frailty, and mortality from too low muscle strength relative to body size. The goal of the study is to assess body composition and physical function in older adults with obesity.
详细描述
This is a cross-sectional study in 40 adults aged 60 to 80 years with obesity. Body composition, physical function, and insulin resistance will be measured. Subjects who satisfy the eligibility criteria and sign the informed consent will be enrolled. Subjects will complete an assessment of body composition by bioelectrical impedance analysis and tests of physical performance. Blood will be drawn for measurement of fasting glucose and insulin.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 60 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Body mass index > 30kg/m2
- •Age 60 - 80 years
排除标准
- •self-reported history of diabetes, or cancer or significant cardiovascular or hepatic or renal disease or dysfunction.
- •clinically significant gastrointestinal malabsorption syndromes such as chronic diarrhea, or celiac disease.
结局指标
主要结局
Fat Mass
时间窗: One day
Measurement of fat mass
Fat-free Mass
时间窗: One day
Measurement of fat-free mass
Modified Physical Performance Test
时间窗: One day
Test for assessing physical performance. The scale ranges from 0 to 36 and higher score indicates a better outcome
次要结局
- Hand Grip Strength(One day)
- 6-minute Walk Test(One day)
- Homeostasis Model Assessment of Insulin Resistance (HOMA-IR)(One day)
研究者
Candida Rebello
Assistant Professor
Pennington Biomedical Research Center