NCT01139333已完成不适用
Evaluation of Mer and Axl Expression in Acute Myeloid Leukemia Patient Samples
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 主要终点
- Expression of Mer and Axl
研究概览
简要总结
RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research study is studying blood and tumor tissue samples from young patients with acute myeloid leukemia.
详细描述
OBJECTIVES:
- To evaluate Mer and Axl expression in samples from pediatric patients with acute myeloid leukemia (AML).
- To determine if abnormal expression of Mer and Axl is associated with poor clinical characteristics (e.g., induction failure or relapse) of AML in these patients.
OUTLINE: This is a multicenter study.
Archived samples from pediatric patients with acute myeloid leukemia are analyzed for Mer and Axl expression by flow cytometry and western blot assays.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Expression of Mer and Axl
Association of abnormal expression of Mer and Axl with induction failure or relapse
次要结局
未报告次要终点
研究者
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