NCT05073601已完成不适用
Thyroid Gland Dysfunction and Vitamin D Receptor Polymorphism in Keratoconus
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 262
- 试验地点
- 1
- 主要终点
- concentration of free T4
研究概览
简要总结
This prospective study the thyroid gland dysfunction and vitamin D receptor polymorphism in keratoconus patients
详细描述
This is a prospective observational study in which blood samples are collected from keratoconus patients looking for thyroid dysfunction and vitamin D levels in the serum and assessing the Vitamin D receptor polymorphism in comparison to healthy control.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •keratoconus patients without previously diagnosed thyroid disorder in comparison to healthy control without known systemic disease and with normal cornea who were selected from candidates of refractive surgery with normal topography
排除标准
- •patients who could not provide informed consent or the necessary samples for any reason, patients with associated other ophthalmic pathologies or systemic disorders were excluded from the study
结局指标
主要结局
concentration of free T4
时间窗: 2 month
ng/dl
concentration of TSH
时间窗: 2 month
milli-international units per liter
concentration of free T3
时间窗: 2month
pg/ml
vitamin D receptor polymorphism
时间窗: 2 month
number of participant with vitamin D receptor polymorphism
次要结局
- serum vit D(2 month)
研究者
Eman Azmy
assistant professor
Mansoura University
研究点 (1)
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