ISRCTN78985727已完成不适用
Effect of epleronone on thrombotic and thrombolytic status in heart failure and coronary artery disease
East and North Hertfordshire NHS Trust (UK)0 个研究点目标入组 105 人开始时间: 2006年10月24日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 105
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Aged 18 to 80 years
- •2. Stable documented CAD or stable HF (functional state New York Heart Association Class II or III) and healthy volunteers
排除标准
- •1. Inability to consent
- •2. Current participation in another study
- •3. Over 80 years and under 18 years
- •4. Acute coronary syndrome within four weeks
- •5. Acute hospital admission with HF in preceding four weeks
- •6. Stroke in the last four weeks
- •7. Insulin-dependent diabetes mellitus
- •8. Renal impairment
- •10. Malignancy
- •11. Bleeding diathesis
- •12. Concomitant medication with clopidogrel, erythromycin, dipyridamole, warfarin, glycoprotein 2b/3a inhibitors, epleronone, spironolactone or angiotensin II antagonists
- •13. When complete follow up over one week period in the judgment of the investigator is unlikely
- •14. Any disease shortening life-expectancy to less than 12 months
- •15. Blood dyscrasia
- •16. Intolerance to or contra-indication to aspirin
- •17. Any contra-indication to Epleronone
研究者
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