Pilot study on the use of albumin function test by ESR method in ICU patients for the detection of sepsis/septic shock and its follow-up.

MedInnovation GmbH0 个研究点目标入组 26 人开始时间: 2021年4月28日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Sepsis Group
•- At least 18 years
•- Patients diagnosed with sepsis as defined by Sepsis-3 (life-threatening organ dysfunction caused by a dysregulated immune response to infection.
•Clinical Criteria: SOFA score =2, screening tool: qSOFA at least 2 of 3 (AF=22/min; RR syst. =100mmHg; impaired mental status: GCS<15).
•Septic shock
•- At least 18 yrs.
•- Septic shock = sepsis + cardiovascular collapse unresponsive to hydration and vasopressors necessary to maintain MAP > 65mmHg, lactate = 2 mmol/L
•Control group
•- At least 18 yrs.
•- Patient -of the intensive care unit of the Internal Medicine of the University Medical Center Rostock without sepsis / septic shock.
•- If sepsis / septic shock occurs within 7 days, the patient will be kept as control group 2, but an additional control patient without sepsis / septic shock will be included in the study
•Translated with www.DeepL.com/Translator (free version)

•Extracorporeal treatment with citrate anticoagulation ongoing at the time of blood collection;
•Albumin substitution;
•More than 500ml of FFP or red cell concentrate 12 hours prior to blood collection;
•Patients with liver cirrhosis;

发起方