NCT06091904招募中不适用
Effects of Sufentanil on the Intraoperative Hemodynamic Parameters in Patients Undergoing Extracranial-intracranial Bypass Surgery: a Prospective Randomized Controlled Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 92
- 试验地点
- 1
- 主要终点
- Intraoperative hypotension
研究概览
简要总结
This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who undergo elective extracranial-intracranial bypass surgery
- •American Society of Anesthesiologists grade 1,2,3
- •Age > 18 years old
排除标准
- •Refuse to participate to the study
- •American Society of Anesthesiologists grade 4
- •Body Mass Index < 18.5 kg/m2 or > 35 kg/m2
- •Allergic history of opioid
- •MAO Inhibitor user
- •Severe respiratory insufficiency
研究组 & 干预措施
sufentanil group
Experimental
sufentanil is administered for analgesic during general anesthesia
干预措施: Sufentanil (Drug)
remifentanil group
Active Comparator
remifentanil is administered for analgesic during general anesthesia
干预措施: Remifentanil (Drug)
结局指标
主要结局
Intraoperative hypotension
时间窗: During surgery
MAP \< 80 mmHg
次要结局
- Incidence of tachycardia(During surgery)
- Incidence of bradycardia(During surgery)
- Minimum systolic blood pressure(During surgery)
- Inotropic requirements(During surgery)
- Maximum systolic blood pressure(During surgery)
研究者
Chang-Hoon Koo
Assistant professor
Seoul National University Hospital
研究点 (1)
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