Screening of Septo-optic Dysplasia During a Fetal Examination at 16-20 Weeks of Gestation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Calculation of average area of OC according to gestational week millimeter square
研究概览
简要总结
Evaluation of prenatal optic chiasm (OC) is important for the differential diagnosis of septo-optic dysplasia (SOD), which is a congenital optic disc anomaly, and the absence of the cavum septum pellucidum (CSP). Septo-optic dysplasia is associated with a wide range of neurological abnormalities, including hypoplasia of the visual pathways, CSP agenesis, and developmental delay.
详细描述
Up to now, optic chiasm measurement were all done in the third trimester. in the present study, OC will be measure directly in a 2D ultrasound in coronal plane within the second trimester. In fetuses with SP agenesis, the morphology and width of the OC visual pathway may be a suitable tool to assess its development. It can also assist in the difficult task of providing prenatal counseling when faced with a diagnosis of CP agenesis. therefore In the present study, it was planned to show the optic chiasm in the screening of septooptic dysplasia by ultrasound between 16-20 weeks of gestation, and to measure the optic chiasma width and length, and to determine the mean values in the second trimester.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •aged greater than 18 years old
- •having singleton pregnancy
排除标准
- •being under the age of 18
- •having IVF pregnancy
- •having multiple pregnancy
- •comorbidity during pregnancy
- •smoking history
- •presence of familial genetic disease
结局指标
主要结局
Calculation of average area of OC according to gestational week millimeter square
时间窗: 2 months
Calculation of average width of OC according to gestational week in millimeter
时间窗: 2 months
Calculation of average height of OC according to gestational week in millimeter
时间窗: 2 months
次要结局
未报告次要终点
研究者
Süleyman Salman
Associate Professor
Gaziosmanpasa Research and Education Hospital
