To study the effect of instillation of intraperitoneal Bupivacaine (0.25%) to achieve postoperative analgesia in patients undergoing Laparoscopic cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- Other
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Proportion of patients having Visual Analog Score(VAS)3 at 3hours
研究概览
简要总结
My Thesis is to study the effect of instillation of intraperitoneal Bupivacaine (0.25%) to achieve postoperative analgesia in 50 patients undergoing Laparoscopic Cholecystectomy. Patients belonging to ASA grade I-II, aged 18year to 60years, weighing between 45-85 Kgs, undergoing Laparoscopic Cholecystectomy under General Anaesthesia are selected for the study.
After removal of gallbladder and haemostasis achieved, residual blood and fluid will be thoroughly suctioned. The surgeon will instill 40ml of 0.25% Bupivacaine in the subdiaphragmatic suprahepatic surface of liver and gall bladder. In the postoperative period, we observe the duration of analgesia using Visual Analog Score, hemodynamic variables, 24 hours analgesic requirement, and any side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade I-II Age 18 – 60 years Weight 45-85Kg A patient undergoing Laparoscopic Cholecystectomy under General Anaesthesia.
排除标准
- •Needing bile duct exploration, insertion of a T-drain.
- •Acute cholecystitis.
- •Surgery-related complication example, bile spillage or conversion to open cholecystectomy Duration of surgery exceeded 2 hours.
- •Severe systemic disease.
- •Prolong Analgesics ingestion Allergy to local anesthetics.
结局指标
主要结局
Proportion of patients having Visual Analog Score(VAS)3 at 3hours
时间窗: Proportion of patients having Visual Analog Score(VAS)3 at 3hours
次要结局
- Duration of analgesia(Haemodynamic Variables such as Heart Rate (HR), Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP))