Bodyweight Interval Exercise in the Fed Versus Fasted State on Postprandial Glycemia, Appetite Perceptions and Fat Oxidation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Average blood glucose concentration
研究概览
简要总结
The purpose of this study is to investigate the effects of a single session of at-home bodyweight interval exercise, performed in the fasted or fed state, on postprandial glycemic management, post-exercise fat oxidation, and overall perceptions of appetite in recreationally active females. This is a remote/online study and does not involve any visits to the laboratory.
详细描述
Following the acquisition of informed consent via videoconferencing, eligibility to participate in the study will be determined using questionnaires. If inclusion criteria is met, participants will undergo virtual exercise familiarization by following a pre-recorded instructional video.
Eligible participants will be assigned, in a random order, to two metabolic trials at least 3 days apart in the follicular phase of the same menstrual cycle. These visits will be online with an investigator on videoconferencing. The two trials involve: 1) Exercise followed by breakfast; and 2) Breakfast followed by exercise.
Various outcomes will be measured throughout the metabolic trials including: blood sugar, fat oxidation and appetite. All research tools needed to acquire these methods will be delivered to participants' place of residence.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Females 18-35 years
- •Recreationally active (complete <150 min of exercise 1-3 days per week) and not training for any specific sport
- •Experiencing monthly menstrual periods (eumenorrheic)
- •Are not currently on oral contraceptives, or are taking triphasic oral contraceptives
- •Body mass index (BMI) ≥18.5 kg/m2 and ≤30 kg/m2
- •Regular consumption of a breakfast meal (solid and liquid meals apply) most (≥ 4) days of the week
- •Have a device compatible for use with study applications (e.g., smart phone)
排除标准
- •Inability to safely perform physical activity as determined by the Get Active Questionnaire
- •Not willing to consume the standardized test drink before and after exercise
- •Sensitive to meal timing around exercise (e.g., gastrointestinal issues if exercise performed 10 min after the start of meal consumption or if a meal is consumed 5 min after exercise)
- •Inability to adhere to pre-trial protocol guidelines (e.g., caffeine or alcohol restrictions)
- •Physical limitations for bodyweight exercise
- •Are on monophasic or biphasic oral contraceptives
- •Regular tobacco or cannabis use (e.g., recreational and/or medical cannabis, cigarettes, e-cigarettes, vape pens, JUUL)
- •Regular use of drugs that may alter metabolism (e.g., corticosteroids, nSAIDs)
- •Diagnosed medical condition under the care of care of a physician (e.g., type 2 diabetes, cardiovascular disease) Currently enrolled in a course with Dr. Gillen
研究组 & 干预措施
Fed Exercise
Breakfast followed by exercise
干预措施: Fed exercise (Other)
Fasted Exercise
Exercise followed by breakfast
干预措施: Fasted exercise (Other)
结局指标
主要结局
Average blood glucose concentration
时间窗: 2 hours
Average blood glucose concentration during postprandial period
次要结局
- Blood glucose concentration(2 hours)
- Blood glucose area under the curve(2 hours)
- Peak blood glucose concentration(2 hours)
- Post-exercise fat oxidation(pre-exercise, immediately post-exercise, up to 3 hours post-exercise)
- Appetite Perceptions(pre-exercise, immediately post-exercise, and 1, 2 and 3 hours post-exercise)
研究者
Jenna Gillen
Assistant Professor
University of Toronto