Transversus Abdominis Plane (TAP) Block for Laparoscopic Appendicectomy in Children: Opioid Saving and Alternative in the Curarization
试验速览
- 阶段
- 不适用
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Painkiller of help consumption
研究概览
简要总结
The transversus abdominis plane (TAP) block is a regional anesthetic technique for post operative pain control after abdominal surgical procedures. Its effectiveness in children undergoing laparoscopic appendectomy has not been demonstrated. The investigators evaluate its analgesic efficacy over the first 24 post operative hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 1 Year 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient hospitalized in surgery and infantile anesthesia unit or admitted in emergencies for an laparoscopic appendectomy surgery.
- •Patient whose general state corresponds to the classification of the American Society of Anesthesiologists (ASA) I to II
- •Patient member in a national insurance scheme
排除标准
- •Patient with drilled appendicitis or peritonitis
- •Patient with a contraindication to local anesthesics
- •Patient with a contraindication to TAP block
- •Patient with allergies or known hypersensitivity to curare
研究组 & 干预措施
Group 1
Curare: Atracurium injection at 0.5 mg/kg
干预措施: Curare (Drug)
Group 2
TAP block and curare: Ultrasound-guided transversus abdominis plane block wih Ropivacaine injection 0.2% at 0.3 ml/kg then atracurium injection at 0.5 mg/kg
干预措施: TAP block with Ropivacaine (Other)
Group 2
TAP block and curare: Ultrasound-guided transversus abdominis plane block wih Ropivacaine injection 0.2% at 0.3 ml/kg then atracurium injection at 0.5 mg/kg
干预措施: Curare (Drug)
Group 3
TAP block: Ultrasound-guided transversus abdominis plane block wih Ropivacaine injection 0.2% at 0.3 ml/kg
干预措施: TAP block with Ropivacaine (Other)
结局指标
主要结局
Painkiller of help consumption
时间窗: up to 24 hours after surgery
Quantity of analgesic of help (Nalbuphine, Nubain®, Dupont Pharma, Paris, France) taken after the surgery.
次要结局
- Pain intensity after surgery(up to 24 hours)
- First demand of analgesic of help(up to 12 hours)