Pre-emptive Ultrasound Guided Superior Hypogastric Plexus Block in Pelvic Cancer Surgeries : a Randomized Double-Blinded Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- morphine consumption
研究概览
简要总结
The superior hypogastric plexus (SHP) is a retroperitoneal structure with a predominance of afferent sympathetic nerve fibers. The perception of central pelvic pain is thought mainly to involve transmission through this plexus. Therefore, blocking or of SHP has been used to treat pelvic pain.
详细描述
Ultrasound guided superior hypogastric plexus block there is 2 equal groups:
Group S (SHPB group 18 patients) ultrasound guided SHPB is done after induction of balanced general anesthesia (fentanyl, propofol and rocuronium) using 20 ml Bupivacaine 0.5% before skin incision, Group C (Control group 18 patients) in which same technique will be done but using normal saline 0.9% instead of bupivacaine. Patients of both groups will receive patient controlled analgesia using morphine with continous background infusion of morphine 1.5 mg/h with adding granisterone 2mg/60 ml and ability to give bolus of 0.5 mg morphine on demand.
• Dosing and administration; Group S (SHPB group 18 ultrasound guided SHPB ) using 20 ml Bupivacaine 0.5% before skin incision.
Group C (Control group 18 patients) in which same technique will be done but using normal saline 0.9%
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
盲法说明
Randomization is done using computer generated sequence. Concealment will be achieved by opaque envelope.
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA II,III.
- •Patients undergoing pelvic surgeries.
排除标准
- •Patients refusal,
- •Coagulopathy,
- •Infection.
结局指标
主要结局
morphine consumption
时间窗: baseline till 24 hours postoperative
Total 24 hours morphine consumption in milligrams
次要结局
- Visual analogue scale (VAS)(Visual analogue scale (VAS) at baseline till 24 hours postoperative)
研究者
Mohammed Abdelfattah Abdelwadod
Mohammed Abdelfattah Abdelwadod
National Cancer Institute, Egypt