Oscillating Positive Expiratory Pressure Therapy Versus Autogenic Drainage in Patients With Chronic Obstructive Pulmonary Disease: Effects on Pulmonary Function, Sputum Clearance, Dyspnea, and Quality of Life
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Change in Forced Expiratory Volume in 1 Second (FEV₁ % Predicted)
研究概览
简要总结
Chronic Obstructive Pulmonary Disease (COPD) is a long-term lung condition that causes breathing difficulty, cough, and sputum production. Airway clearance techniques are commonly used to help reduce symptoms and improve breathing in patients with COPD.
This study compared two airway clearance methods-oscillating positive expiratory pressure (OPEP) therapy and autogenic drainage-to determine which method is more effective in improving lung function, sputum clearance, shortness of breath, and quality of life in patients with COPD.
Participants were divided into two groups and received either OPEP therapy or autogenic drainage for four weeks. Outcomes were measured at the beginning of the study and again after completion of the intervention. The findings of this study aim to support evidence-based physiotherapy management for patients with COPD.
详细描述
This study was a comparative interventional clinical trial conducted to evaluate the effects of oscillating positive expiratory pressure therapy versus autogenic drainage in patients diagnosed with Chronic Obstructive Pulmonary Disease. Ethical approval was obtained from the institutional ethics review committee prior to study initiation, and written informed consent was obtained from all participants.
Eligible participants with stable COPD were enrolled and allocated into two intervention groups. Baseline assessments were performed prior to the initiation of treatment. Participants in the first group received oscillating positive expiratory pressure therapy as part of their airway clearance regimen, while participants in the second group were treated using autogenic drainage techniques. Both interventions were administered over a four-week period.
Outcome measures were assessed at two time points: baseline (pre-intervention) and after completion of the four-week intervention period. Pulmonary function was evaluated using spirometry. Sputum clearance was assessed using the Breathlessness Cough Sputum Scale (BCSS). Dyspnea was measured using the Modified Borg Dyspnea Scale, and quality of life was assessed using the COPD Assessment Test (CAT).
The results of this study aim to compare the effectiveness of the two airway clearance techniques and provide evidence to guide clinical decision-making in the physiotherapy management of patients with COPD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome assessors were blinded to group allocation to minimize assessment bias. Participants and care providers were not blinded due to the nature of the interventions.
入排标准
- 年龄范围
- 35 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 35 and 50 years
- •Both genders
- •Participants must have a confirmed diagnosis of Chronic Obstructive Pulmonary Disease (COPD) based on the GOLD 2023 guidelines
- •Clinically stable
- •History of Sputum Culture
排除标准
- •Acute exacerbation of COPD
- •Severe cardiovascular, neurological, or musculoskeletal disorders
- •Recent thoracic or abdominal surgery
- •Presence of other significant respiratory diseases
- •Unwillingness to participate or inability to comply with the study protocol
研究组 & 干预措施
Oscillating Positive Expiratory Pressure Therapy Group
Participants in this group received oscillating positive expiratory pressure therapy as an airway clearance technique for four weeks.
干预措施: Oscillating Positive Expiratory Pressure Therapy (Device)
Autogenic Drainage Group
Participants in this group received autogenic drainage as an airway clearance technique for four weeks.
干预措施: Autogenic Drainage (Behavioral)
结局指标
主要结局
Change in Forced Expiratory Volume in 1 Second (FEV₁ % Predicted)
时间窗: Baseline and at 4 weeks
Pulmonary function was assessed using spirometry by measuring forced expiratory volume in one second (FEV₁), expressed as percentage of the predicted value, in patients with Chronic Obstructive Pulmonary Disease.
次要结局
- Change in Sputum Clearance as Measured by the Breathlessness, Cough, and Sputum Scale (BCSS)(Baseline and at 4 weeks)
- Change in Dyspnea Severity as Measured by the Modified Borg Dyspnea Scale(Baseline and at 4 weeks)
- Change in Health-Related Quality of Life as Measured by the COPD Assessment Test (CAT)(Baseline and at 4 weeks)
研究者
Adnan Hashim
Doctor of Physical Therapy Student
University of Lahore