Evaluation of clinico-pathological characteristics, prognostic factors and treatment outcomes in patients with osteosarcoma in children and adults treated in India

Osteosarcoma is the most common bone sarcoma, most commonly affecting children and adolescents. The management of osteosarcoma has evolved to a point where the 5 years survival rates are above 70 %. Though these advancements are reflected in the data from some Indian studies as well (even if the outcomes still lag behind those of international studies), these studies are largely limited only to some centres in major Indian cities.

Across the globe, apart from single centre studies, the outcome of osteosarcoma has been studied in many prospective and retrospective multicentric studies as well. The contribution of these multicentric studies has been invaluable in understanding the outcome of osteosarcoma management and, even more importantly, making of policies and guidelines and allocation of resources. This becomes even more important in the Indian context, to be able the gauge uniformity and patterns of treatment, gaps in promptness of referral and initiation of treatment, availability (or lack) of specialized orthopaedic oncology units across centres, protocols of chemotherapy being followed across various centres and abandonment of treatment. Such a study would also provide more insight into, and indigenous solutions to, the problems faced by LMIC countries.

This retrospective observational multicentric study, under the aegis of IMSOS, aims to analyse the demographics, characteristics and oncological outcomes of management of osteosarcoma in Indian patients treated in centres across India, diagnosed from 2001till date. The participating centres will be invited to fill up the details in the attached Google survey form. All patients will then be analysed for demographic, clinicoradiological and pathological details, management details and oncological outcomes. The aim of this study will be to study demographic and treatment patterns of osteosarcoma in India and attempt to correlate these with oncological outcomes of these patients.