Therapeutic Evaluation Of Marham-e-Dafe-Shiqaq-al-Maqad In Case of Shiqaq-al-Maqad(Anal Fissure)
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Improvement in
研究概览
简要总结
Title:
Therapeutic Evaluation of Marham-e-Dafe Shiqaq-al-Maqad in Case of Shiqaq-al-Maqad (Anal Fissure)
Researcher:
Dr Saquib Raza PG Scholar Department of Ilmul Jarahat
State Takmeel-ut-Tib College and Hospital Lucknow
Overview:
This clinical research aims to evaluate the effectiveness of a traditional Unani formulation—Marham-e-Dafe Shiqaq-al-Maqad—for treating anal fissures a common and painful anorectal condition
Objectives:
Prevent surgical intervention and associated complications
Assess the healing efficacy of the Unani ointment and laxative combination.
Halt progression of acute fissures into chronic ones.
Methodology:
Design: Open-label single-arm interventional clinical study
Sample Size: 30 patients (18–60 years)
Duration: 6 weeks
Treatment:
Topical: Marham-e-Dafe Shiqaq-al-Maqad (BD)
Oral: Safoof Mulaiyyan (5g at bedtime)
Assessment Tools: Clinical exam Visual Analogue Scale (VAS) for pain rectal examination
Inclusion/Exclusion: Patients with simple anal fissures included other anorectal or systemic conditions excluded
Outcomes:
Measured through symptom relief (pain bleeding constipation healing of fissure and safety parameters (blood tests)
Significance:
The study explores a cost-effective side-effect-free alternative from Unani medicine for managing anal fissures especially chronic ones resistant to conservative modern treatments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Clinically diagnosed cases of Shiqaq-al-Maqad (Anal Fissure) (anterior & posterior) Patients irrespective of sex religion occupation & economical status Patients of both the sexes in between the age group of 18 to 60 years.
排除标准
- •Anal Fistula External sphincter deffect Haemorrhoids Rectal Prolapse Anal/perianal abscess Anal Fissure secondary to Ulcerative colitis Syphilis, Crohn’s disease Tuberculosis and malignancy of rectum and anal canal Pregnancy Advanced Anal Fissure Venereal diseases Severe anaemia Mentally Retarded Patients.
结局指标
主要结局
Improvement in
时间窗: Clinical assessment will be done at 0,14th, 28th & 42nd days.
Pain during & after defection
时间窗: Clinical assessment will be done at 0,14th, 28th & 42nd days.
Constipation
时间窗: Clinical assessment will be done at 0,14th, 28th & 42nd days.
Per rectal bleeding
时间窗: Clinical assessment will be done at 0,14th, 28th & 42nd days.
次要结局
- Diagnosed by simple rectal examination(Visual Analogue Scale (VAS))
研究者
DR SAQUIB RAZA
State Takmeel ut Tib College And Hospital