The Effect of Autogenous Tooth Roots for Lateral Alveolar Ridge Augmentation and Staged Implant Placement (A Controlled Clinical Study With Histological Assessment)
试验速览
- 阶段
- 4 期
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Clinical and radiographic assessment of alveolar bone width following autogenous tooth roots augmentation.
研究概览
简要总结
assess and compare the efficacy and safety of autogenous tooth roots for lateral alveolar ridge augmentation with staged implant placement in comparison to autogenous bone block.
详细描述
A total of 14 patients in need of implant therapy and lateral ridge augmentation were allocated to parallel groups receiving either 1) healthy autogenous tooth roots (e.g. retained wisdom or impacted teeth or 2) cortical autogenous bone blocks harvested from the retromolar area. After 26 weeks of submerged healing the horizontal bone gain were assessed both clinically and radiographically. A core biopsy was taken during the implant placement to assess the histology of the newly formed bone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Candidate for lateral ridge augmentation
- •Insufficient bone ridge width at the recipient site for implant placement
- •Sufficient bone height at the recipient site for implant placement
- •Healthy oral mucosa, at least 3 mm keratinized tissue.
- •Presence of wisdom teeth free from periapical infection.
- •Missing maxillary or mandibular tooth with moderate horizontal defect (4-8) according to cologne classification
排除标准
- •Patients are systemically free according to Modified Cornell Medical Index 2) smokers patients. 3) Pregnant or lactating women.
研究组 & 干预措施
Autogenous bone block
the monocortical block grafts were harvested from the retromolar region (i.e. linea oblique) by using of rotating (i.e. carbide burs)
干预措施: autogenous bone block (Procedure)
Tooth block
In the first group, a second mucoperiosteal flap was elevated to surgically remove the respective wisdom tooth. After its removal and during the same surgery, the crown was decapitated at the cemento -enamel junction using a rotating carbide bur under gentle sterile saline cooling and the exposed pulp was preserved. The separated tooth root was adapted to match the size and shape of the defect area. To improve ankylosis between the graft and the defect site, the layer of cementum at the respective downward aspects of the root was carefully removed using a diamond bur until the underlying dentin was entirely exposed
干预措施: tooth block (Procedure)
结局指标
主要结局
Clinical and radiographic assessment of alveolar bone width following autogenous tooth roots augmentation.
时间窗: 6 months postoperatively
次要结局
- Histological analysis of remodeled autogenous bone roots 4 months following horizontal ridge augmentation. Histological analysis of remodeled autogenous bone roots 4 months following horizontal ridge augmentation.(6 months postoperatively)
研究者
Doaa Adel Salah Khattab
Lecturer Periodontology, Faculty of Dentistry
Ain Shams University